The extracts of red yeast rice (RYR) represent a nutraceutical with proven cholesterol lowering effect. The monacolin K found in RYR is a safe and effective supplement for managing mild to moderate hypercholesterolemia. The powerful antioxidant coenzyme Q10 can lower LDL hepatic metabolism of fats, which lowers LDL levels in blood (LDL is also known as bad cholesterol). Naringenin, which is responsible for the bitter taste of grapefruit stimulates hepatic metabolism of fats, which make lower LDL levels. In addition, the high fiber content of grapefruit keeps cholesterol in the digestive tract and helps to eliminate the excess cholesterol out of the body. Red grape fruit extract also helps manage the cholesterol level. It supports the antioxidant activity and the body’s ability to control blood sugar level. Vitamins B also regulate the cholesterol and bile acid synthesis as well as the triglycerides metabolism. Vitamins B are involved in the transformation of lipoproteins and metabolism of cholesterol incorporated into lipoproteins. By increasing the production of bile acids, they can reduce the level of cholesterol entering the bloodstream. Thus, they contribute to the reduction of the risk of developing arteriosclerosis (hardening and narrowing of the arteries).